The combination of hyaluronic acid with the biological and anti-inflammatory effects of platelet-rich plasma is the Cellular Matrix (A-PRP–HA) preparation. In this medicine, hyaluronic acid and platelet-rich plasma act synergistically, restoring homeostasis in the joint and, by protecting cartilage, relieving pain. Hyaluronic acid is an important component of healthy synovial fluid. A network of hyaluronic-acid chains forms an ideal cellular matrix.
Application of Cellular Matrix in dermatology represents a natural form of skin rejuvenation using one's own growth factors. Biostimulation of skin cells is achieved through injections of bio-active platelet-rich plasma (PRP) obtained from one's own blood. Hyaluronic acid and platelet-rich plasma (PRP) in the Cellular Matrix preparation lead to regeneration and rejuvenation of the skin, improvement of skin tone, texture and hydration, as well as significant reduction of wrinkles and skin laxity. The result of this therapy is a natural, radiant and youthful appearance. This preparation is also used for the treatment of hair loss, as well as for the treatment of thinning hair in men and women.
The method of injecting autologous platelet-rich plasma into the intimate region – the vagina and labia majora – involves PRP (platelet-rich plasma) treatment. It is a natural method based on the regenerative capacity of growth factors from platelets in the patient’s own blood. During injection, platelet growth factors support formation of new collagen and blood vessels, as well as restoration and improvement of damaged skin, thus slowing and eliminating signs of ageing. Where a prolonged effect is desired, PRP sets with added hyaluronic acid, namely Cellular Matrix, are used. This rejuvenation procedure stimulates tissue regeneration through growth factors and intensively hydrates the skin at depth using hyaluronic acid. Cellular Matrix is a method that achieves additional volume and increases vaginal elasticity, especially after childbirth and in cases of vaginal dryness or scars after episiotomy.
Application of Cellular Matrix (hyaluronic acid and platelet-rich plasma PRP) in rheumatology and orthopaedics:
The combination of hyaluronic acid with the biological and anti-inflammatory effects of platelet-rich plasma is a preparation Cellular matrix (A PRP - HA). In this medicine, hyaluronic acid and platelet-rich plasma act synergistically, restoring homeostasis to the joint and, by protecting the cartilage, relieving the patient’s pain. Hyaluronic acid is an important component of healthy synovial fluid. The network of hyaluronic acid chains represents an ideal cellular matrix. The key role of this preparation is in the synthesis of a new matrix for tissue regeneration. Autologous platelet-rich plasma (A-PRP) is an internal reservoir of growth factors from the patient's own blood. After intra-articular administration, an anti-inflammatory effect occurs and activation of signal cells takes place, which trigger a cascade reaction, leading to stimulation of cell migration and differentiation.
The drug preparation procedure is as follows: after withdrawing 4ml of blood, autologous platelet-rich plasma is obtained through a special procedure, which is mixed in a closed system with 40mg of hyaluronic acid. The prepared preparation is applied to the patient's joint, and immediately a cellular network of hyaluronic acid is created in which platelets are dispersed. Compared to A-PRP, this drug has significantly higher viscosity, and thus a greater effect on increasing mobility and reducing pain.
Application of Cellular Matrix (hyaluronic acid and platelet-rich plasma PRP) in dermatology:
Application of Cellular Matrix in dermatology represents a natural form of skin rejuvenation using one's own growth factors. Biostimulation of skin cells is achieved through injections of bio-active platelet-rich plasma (PRP) obtained from one's own blood.
Soon after application, stimulation of collagen and elastin synthesis occurs, increased blood flow through the skin, and increased anti-oxidative activity due to the effects of growth factors from one's own blood.
Hyaluronic acid and platelet-rich plasma (PRP) in the Cellular matrix preparation lead to skin regeneration and rejuvenation, improvement of skin tone, texture and hydration, as well as significant reduction of wrinkles and skin laxity. The result of this therapy is a natural, radiant and youthful appearance. This preparation is also used for the treatment of hair loss, as well as for the treatment of thinning hair in men and women.
Procedures for the application of PRP and Cellular Matrix in regenerative, aesthetic and functional gynaecology:
Aesthetic gynaecology is a relatively new term in modern medicine, but looking through history, the term cosmetic gynaecology appears as early as the Middle Ages. Since ancient times, people have been intrigued by sexuality, and thus the genitalia have been a subject of interest.
Aesthetic, regenerative and above all functional gynaecology represents the newest and fastest growing branch of gynaecology which aims not only at the visual aspect of intimate parts, but also the functional aspect in terms of improving sensation and reducing discomfort, with increased enjoyment in intimate relations and raising the quality of life, especially after childbirth and during the perimenopausal and menopausal periods.
PRP and Cellular matrix, vaginal fillers use completely natural mechanisms of our organism to reduce vaginal dryness and alleviate symptoms of involuntary urine leakage. Vaginal fillers restore moisture and increase elasticity, stop time by reducing symptoms that come with ageing.
Aesthetic or functional gynaecology is recommended for women of all ages. The best effect is achieved when it is done preventively.
This area of gynaecology is revolutionary in increasing and restoring the quality of life for the modern woman. With emancipation and the breaking down of taboos, women have become aware of their sexuality and deserve to have a quality life in every sense in the 21st century, regardless of age. Aesthetic gynaecology should be experienced as hygiene of the genital region, which is not a luxury but a necessity.
What is PRP treatment of the vagina, and what is Cellular matrix?
PRP (platelet rich plasma) treatment is a natural method based on the regenerative ability of growth factors from platelets of one's own blood. This is a method of injecting one's own platelet-rich plasma into the intimate region – vagina and labia majora.
Platelets contain numerous growth factors and bioactive proteins that affect tissue regeneration. Upon injection, platelet growth factors assist in the formation of new collagen and blood vessels, as well as the renewal and improvement of damaged skin, thereby slowing down and eliminating signs of ageing.
For a longer-lasting effect, PRP sets with hyaluronic acid, i.e. Cellular Matrix, are used. This rejuvenation procedure stimulates tissue regeneration through growth factors and deeply hydrates the skin through hyaluronic acid. Cellular Matrix provides additional volume and may enhance the sensation of vaginal tightening and elasticity, as well as enjoyment in intimate relations.
After the intervention the patient can return to her daily activities.
For whom are vaginal PRP and Cellular Matrix recommended?
For all women with vaginal and external genital dryness; painful sexual intercourse; absence of orgasm and reduced vaginal sensitivity; urinary urgency and involuntary urination; lichen sclerosus (an autoimmune skin condition); vaginal laxity after childbirth; or pronounced episiotomy scars.
In consultation with your doctor and depending on the specific symptoms, PRP or Cellular Matrix is recommended.
Which regions in gynaecology can be treated?
Labia majora and minora, entrance to the vagina, vaginal walls, perineum and area around the urethra, G spot and clitoris.
What does the procedure involve and how long does it last?
Treatment does not require special patient preparation, there are no contraindications, it lasts about 30-40 minutes and is performed under local anaesthesia. 5 ml of blood is taken from the patient, which is centrifuged, and the resulting platelet-rich plasma (PRP) is applied to selected parts of the intimate region.
Cellular Matrix is prepared in the same way: 5 ml of the patient’s blood is collected and centrifuged to obtain PRP, which is then administered with hyaluronic acid in selected areas of the intimate region.
How many interventions are required?
Treatment is performed usually three times, at monthly intervals, but the number is determined after monitoring the results and is individual to each patient, depending on the initial condition and the body’s response.
Is special care necessary after treatment?
For the next two weeks after the intervention, it is recommended to refrain from sexual intercourse and avoid heavier physical activities.
How are the achieved results maintained?
Treatments can be repeated as needed. It is recommended to repeat this procedure between 18 and 24 months, and it may occur earlier.
Poliklinika Živanović is a licensed institution for the application of Cellular Matrix therapies as a new health technology, which was approved by the Ministry of Health of the Republic of Serbia.